The Coupled Model Intercomparison Project (CMIP) is a standard experimental protocol for studying the output of coupled atmosphere-ocean general circulation models (AOGCMs). CMIP provides a community-based infrastructure in support of model diagnosis, validation, inter-comparison, documentation and data access. Observational metrics based on NASA data have been developed and effectively applied in the previous CMIP5 and post-CMIP5 model evaluation and improvement projects. As new physics and parameterizations continue to be included in models for the upcoming CMIP6, we are developing new methodologies to better constrain models with NASA satellite observations and support CMIP6 model assessments. We target parameters and processes related to atmospheric clouds and water vapor, radiative budget, climate feedbacks, and water and energy cycles, and thus reduce uncertainties in climate models.